BIO-1 Lecture Notes - Lecture 7: Glycosylation, Endomembrane System, Covalent Bond
Document Summary
Transport of vesicles proteins from aggregating and promotes proper folding disulfide bonds here, glycosylation starts here) if they are not properly assembled) After translation on ribosomes all proteins are processed: membrane then transport by vesicular traffic to golgi, etc. ) Entry point for proteins into secretory pathway (via co-translation transfer across rer. Site of protein folding by chaperone proteins that prevent hydrophobic domains of. Site of post-translational modifications of proteins (eg. protein disulfide isomerase forms. Quality control site checks for defective proteins (proteins are not exported from the er. In the er/golgi (proteins of endomembrane system) Protein molecules are targeted to specific destinations, vesicle must take the correct cargo. Each bud has a distinctive vesicle coat (copi, copii, and clathrin) Cop-coated vesicles are involved in transport of vesicles from er golgi and within. Clathrin-coated vesicles carry proteins from golgi cell surface or from cell surface . Cargo receptor, adaptin, coat protein, and dynamin.
