NUR 300 Lecture Notes - Lecture 14: Respiratory Alkalosis, Metabolic Alkalosis, Metabolic Acidosis

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10 Dec 2016
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Normal serum ph is maintained within a very narrow range of 7. 35 -7. 45. Ph >7. 8 or <6. 8 is incompatible with life. Disorders in any of these systems leads to alterations in blood ph. Physiologic buffers: bicarbonate carbonic acid buffer system. H + hco3 h2co3 h2o + co2. Hemoglobin (w/o this venous blood would be ph 4. 5: bone: reservoir of bicarb and phosphate. Acidosis: a physiologic process that accruing alone tends to cause academia. : metabolic acidosis from ketoacid production in dka. Alkalosis: a primary physiologic process that occurring alone, tends to cause alkalemia i. e. : respiratory alkalosis from hyperventilation. Acids releases hydrogen ions; bases (alkaline substances) take up h ions. Degree of acidity is reported as ph. Ph scale: 1. 0 (very acid) to 14 (very base) Ph of 7. 0 is neutral: normal arterial blood is 7. 35 to 7. 45. Acid production by cells carbonic acid: co2 + h2o h2co3 h + hco3 (bicarb)

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