NURS 4526 Lecture Notes - Lecture 4: Renal Tubular Acidosis, Lactic Acidosis, Alkalosis
Document Summary
Acid-base balance ph = measurement of acidity or alkalinity of blood. Inversely proportional to # of h+ ions; h+ = ph (acidic); h+ = ph (alkalotic) Normal blood ph = 7. 35 7. 45; midpoint of 7. 4: ph <6. 8 or > 7. 8 leads to death. Pao2: reps amt of o2 dissolved in plasma and is expressed in mmhg: normal pao2: 80-100 mmhg. If the ph is too high (>7. 45) or too low (<7. 35) the speed of chemical rxns become inappropriate for proper cell fxning. Persistent alterations in ph will lead to signs & symptoms, illness, & possibly death, as homeostasis is not maintained. Diminished response to effects and actions of certain medications. Buffers react immediately; rr system responds in minutes and reaches max effectiveness in hrs; renal response takes 2-3 days to respond max but kidneys can maintain balance for longer period.
