PSYCH 212 Lecture Notes - Lecture 75: Umbilical Cord, Limbic System, Dsm-5
Document Summary
Birth records show mothers of later schizophrenia patients experienced more complications in labor and delivery such as: May reduce availability of oxygen to newborn"s brain. Schizophrenia affects many different regions of the brain, but generally with the disorder: Have lower total volume of brain tissue overall. Have enlarged ventricles (fluid-filled cavities in brain) Decreased size of limbic system, a set of brain areas responsible for regulation of emotion and integration of thought and feeling. Malfunctioning temporal roles (perceiving and creating speech) Decreased frontal lobe and temporal lobe activity. Proposal that those with schizophrenia may have overactive or excessive dopamine activity in the limbic system. Likely due to high numbers of postsynaptic dopamine d2 receptors. Yet recent research suggests many aspects of schizophrenia cannot be attributable to only excess dopamine reactivity. Current hypotheses implicate many nts and their interactions. Ex: serotonin and dopamine interactions, gaba (nt that inhibits next cell) and glutamate (activates next cell)
