BIOL 230W Lecture Notes - Lecture 26: Citric Acid Cycle, Acetyl-Coa, Gluconeogenesis

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28 Oct 2016
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Converted to acetyl coa: occurs between glycolysis and krebs cycle. Can be used in another pathway associated with energy other than krebs cycle: fermentation, no oxygen (anaerobic) Steps 1, 3, 10 prevent pathway from proceeding backwards because they are not at equilibrium. Coupled reactions: use atp to drive reactions. Cells can synthesize glucose during times of energy demand and no glucose is available for use. Only liver cells can undergo this process in humans. Glucose can be transported to other cells: muscle, brain. Must use alternative pathways at steps 1, 3, 10. Prevent both from happening at the same time. Steps at equilibrium: concentrations of reactants and products determine the direction of the reaction: delta g is negative, enzymatic activity works to maintain equilibrium. If concentration of reactants increases, then the concentration of the products will also increase: le chatelier"s principle. Irreversible reactions: rate of reaction is regulated through allosteric control: delta g is equal to 0.

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