BIO 111 Lecture Notes - Lecture 7: Pyruvate Dehydrogenase, Acetyl-Coa, Cellular Respiration

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29 Sep 2016
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+ heat: glycolysis occurs in cytosol, breakdown of pyruvate to an acetyl group, citric acid cycle occur in mitochondria, oxidative phosphorylation. ** know input and output of each stage*: glycolysis. Can occur w/ or w/o oxygen: energy investment (raises free energy of glucose) 2 atp hydrolyzed: cleavage (6 c"s to two 3 c"s, energy liberation. Glucose has become 2 pyruvates: breakdown of pyruvate to an acetyl group. Molecule of co2 removed from each pyruvate. Remaining acetyl group attached to coa to make acetyl coa. 1 nadh is made from each pyruvate: citric acid cycle. Acetyl is removed from acetyl coa and attached to oxaloacetate to form citric acid. Steps release, 2co2, 1atp, 3nadh, and 1 fadh2. Oxaloacetate is regenerated to start the cycle again. *** fadh is made is step 6-7 *** succinate to fumarase: oxidative phosphorylation. High energy electrons removed from nadh and fadh2 to make atp. Group of protein complexes and small organic molecules.

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