BIOL 1201 Lecture : BIO NOTES 3
Document Summary
Monday, september 12, 2016. Molecular basis of inheritance. Complementary base pairing (result of hydrogen bonding) Twisted, 1 revolution, 2 backbones. Dna replication involves making dna from dna. (cq) Dna replication occurs in a semi conservative mechanism. (cq) Backbones of dna strands can split under specific heat. Semi conservative molecules lead to mutations. 5" t c c a g g a t g. 5" a t a a c c g g g. Info is based on directionality of backbone. Begins at many origins. Cells cannot divide until they have completely copied dna. Strands must separate and unwind. Builds 5" to 3" in an anti parallel fashion. Dna polymerase- the enzyme that makes dna. Only builds from 5" to 3" anti parallel to the template. When they hit they fuse together. The last molecule to fuse is dna ligase (ability to tie dna pieces together) Small amounts of dna can be repaired but not others. Flow of information within a cell.
