FAM &CS 21 Lecture Notes - Lecture 11: Axon Hillock, Exocytosis, Myelin

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The inside of the membrane becomes positively charged in relation to the outside how neurons transfer information from one location to another from the axon hillock to the axon terminal. During an action potential, the membrane potential briefly becomes positive. Action potential can be explained by the movement of ions through channels that are gated by changes in the membrane potential. Phases of action potential= electrical transmission: resting potential/threshold. Membrane potential where the voltage gated sodium channels open. Selective: favor sodium over potassium because sodium channels have a filter that make them more permeable to sodium than potassium. They open/close because of changes in voltage = -55mv. Na+ is attracted to the inside of the membrane which has a negative electrical potential. New sodium coming in through the open sodium channels. The sodium influx goes everywhere because of diffusion. This causes depolarization (the inside of the membrane becomes less negative)

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