PSY 433 Lecture Notes - Lecture 37: Thalamus, Psychoactive Drug, Psy
29 Jul 2020
Department
Course
Professor
Document Summary
Behavioral and cognitive improvements observed in adhd with psychostimulants are related to changes in neurotransmission in neuroanatomical circuits involved in care. Namely: the lower parietal cortex, theupper emporal t, the caudate core, the putamen and the pale balloon. These structures, mainly involved in motor execution, are connected to areas of the hippocampus responsible for stimulating coding and memory processes. Changes in neurotransmission occur mainly in dopamine and norepinephrine, both in intersynopatic space. Methylphenidate would act by activating the dopaminergic systemor by inhibiting the reuptake of dopamine and amphetamines would act by activating the noradrenergic system by releasing norepinephrine in the hippocampus. However, despite the large number of studies, its mechanism of action is not clear tothe very. In fact, there are some contradictory aspects between adhd physopathology evaluated through neuroimaging techniques such as pet and the changes observed with the administration of psychostimulants.
