BIO 122 Lecture Notes - Lecture 6: Cell Wall, Second Messenger System, Cell Signaling
30 May 2018
School
Department
Course
Professor
Prior to Week 6 Class 1 – Chapter 11 – Cell-Cell Interactions
Know
• What the extracellular matrix is and examples of ECM proteins
o Extracellular matrix is a net of proteins and fibers outside the cell membrane
o Laminin
▪ Connect ecm and cells
o Fibronectin
▪ Connect ecm and cells
o Collagen
▪ Provides tensile strength
o Elastin
▪ Stretch and recoil
• The difference between the primary and secondary cell wall of the plant
o Primary
▪ Thin flexible
▪ Made between new cells
▪ Outer layer
▪ Cellulose
▪ Cell shape
▪ Pectins and glycans to keep wall moist
o Secondary
▪ Between primary cell wall and plasma membrane
▪ Cellulose microfibrils
• That polysaccharides and proteoglycans function in extracellular structure and organization
• That cell communication happens in all cell types
• What the five types of intercellular signaling are
o Direct intercellular
▪ Signaling molecules pass through gap junctions
o Contact-dependent
▪ Signaling molecule on one cell binds to receptor on other cell
o Autocrine
▪ Cell releases signaling molecules that bind to receptors on other nearby cells and itself
o Paracrine
▪ Cell releases signaling molecules that can only bind to receptors on other nearby cells
o Endocrine
▪ Hormones, travel long distances across body to deliver signals
• That response to a signal requires a receptor and what happens after the signal and receptor bind together
o Receptor changes shape to activate signal in cell
• What are the 3 general phases of “signaling”
o 1. Signal reception
o 2. Signal processing/transduction
o 3. Signal response
• What a ligand refers to
o The signaling molecule
• That signals can be hydrophilic or hydrophobic and this directs where they meet their receptor
o Hydrophilic
▪ Lipid-insoluble
▪ Receptor located on membrane surface
o Hydrophobic
▪ Lipid-soluble
▪ Receptor located in the cell
• What the major types of cell-surface receptors are
o The basic structure of a G- protein- receptor complex
▪ Signaling molecule binds to receptor on cell surface
find more resources at oneclass.com
find more resources at oneclass.com
