GEN-3000 Lecture Notes - Lecture 7: Rheumatoid Arthritis, Meddle, Restriction Fragment Length Polymorphism

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7 linkage & chromosome mapping in eukaryotes. Note in this and the following figures that members of homologous pairs of chromosomes are shown in two different colors. This convention was established in chapter 2 (see, for example, Figure 2. 7 and figure 2. 11): meiotic consequences of, independent assortment, linkage without crossing over, linkage with crossing over. 6 the white, miniature (m) mutations (cross b), as compiled by sturtevant. In cross a, 0. 5 percent of the f2 flies (males and females) demonstrate recombinant phenotypes, which express either white or yellow. In (a) the exchange does not alter the linkage arrangement between the alleles of the two genes, only parental gametes are formed, and the exchange goes undetected. 10: each pair must be heterozygous for two alleles, consequences of a double exchange occurring between two nonsister chromatids. Because the exchanges involve only two chromatids, two noncrossover gametes and two double- crossover gametes are produced.

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