GEN-3000 Lecture Notes - Lecture 1: Spindle Apparatus, Sister Chromatids, Dna Replication
Document Summary
Chapter 1: model organisms (importance, early theories of hereditary transmission, pangenesis, specific particles (gemmules) carry information from body to reproductive organs which are passed to embryo at conception, very early concept. Inheritance of acquired characteristics: greek idea, proposed traits acquired in life incorporated into hereditary info and passed on, preformationism. Inside egg or sperm is tiny version of adult: homunculus, blending inheritance, offspring are a blend of parents. James watson, francis crick, and rosalind franklin: 3d structure of dna, 1953, chemical structure of dna resolved, 1966, recombinant dna technology, gilbert and sanger, 1977, developed dna sequence techniques. Round seed vs. wrinkled seed: different alleles occupy the same locus on homologous chromosomes, locus, specific place on a chromosome occupied by an allele, genotype, set of alleles that an individual possesses. Dihybrid cross: crosses of organisms that differ in two characteristics, 9:3:3:1, dominance, types, dominance, 3:1, parents, heterozygous, offspring, a_, aa.