GEN-3000 Lecture Notes - Lecture 1: Pangenesis, Phenotype, Robert Hooke
Document Summary
Principles of heredity first demonstrated 10-12,000 years ago (domestication) Hindu writings 2000 years ago suggest avoiding spouses with undesirable traits. Pangenesis specific particles (gemmules) carry information from body to reproductive organs which are passed to embryo at conception (very early concept) Inheritance of acquired characteristics greeks proposed traits acquired in life incorporated into heredity info and passed on. Ex: artist would pass on art skills to offspring. Robert hooke - 1665, discovered cell using the microscope. Preformationism inside egg or sperm is a tiny version of an adult. Blending inheritance offspring are a blend of parents. Cells are basic unit of all living things. Crossed pea plants and analyzed patterns of transmission. 1885 - heredity information contained in the nucleus. Cut off the tails of mice for 22 generations - tail length of descendants did. Purposed germ-plasm theory - cells of the reproductive system carry not change complete set of information. Genes are the fundamental unit of heredity.