BIOL-242 Lecture Notes - Lecture 37: Acidosis, Ketone Bodies, Sodium Bicarbonate
9 Jun 2020
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Chapter 26 part 1 | acids and bases. Ph affects all functional proteins and biochemical reactions, so closely regulated. Venous blood and if fluid: ph 7. 35. Phosphorus-containing protein breakdown releases phosphoric acid into. Lactic acid from anaerobic respiration of glucose. Fatty acids and ketone bodies from fat metabolism. H+ liberated when co2 converted to hco3 in blood. Concentration of hydrogen ions regulated sequentially by. Chemical buffer systems: rapid; first line of defense. Brain stem respiratory centers: act within 1-3 minutes. Brain triggers respiratory system to breathe slower or faster. Renal mechanisms: most potent, but require hours to days to effect ph changes. Takes a long time to start but very important to ph as liquids can be eliminated through the urine. Hcl + nahco3 h2co3 + nacl. Ph decreases only slightly, unless all available hco3 ( alkaline reserve ) used up. It causes h2co3 to dissociate and donate h+ h+ ties up the base (e. g. oh )
