Biology 1202B Lecture Notes - Lecture 3: Cystic Fibrosis, Neurofibrillary Tangle, Atp-Binding Cassette Transporter
26 Feb 2019
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Mon, jan. 14/19 lecture 3: membrane biology. Introduces double bonds, makes the membrane less saturated and more fluid. Transmembrane protein prediction: non-polar amino acids span the plasma membrane, difference between primary and secondary active transport. Specific: becomes saturated at high concentrations of transported substance (all transporters are used) - all of the proteins are being used - rate is not zero, constant. Add more proteins to plasma membrane to increase the rate of transport - Simple diffusion is linear because there are not proteins to limit the amount of transport. Active transport binding cassette: abc transporters - active transporter. Heterozygote advantage: having only one copy of 508 reduced water loss from cholera and greatly increased chances of survival: with cholera, people had too much cc, therefore releasing too much water. So people with cc had a higher survival rate because they were more resistant to cholera, but increased risk for cf.
