PSL301H1 Lecture Notes - Lecture 1: Oncotic Pressure, Electrophoresis, Thrombin
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Regulates ph, ion concentrations, water levels etch. Restricts fluid loss at injury site using blood clotting factors. Body temp regulation: vasoconstriction vasodilation. Male and female have around the same amount of blood. Can separate the two phases via centrifuging methods, liquid + solid. Plasma: 45-65% of the blood volume, water, ions, trace elements and vitamins , gases (co2, o2, organic molecules; below, amino acids, proteins. Most plasma proteins are made by the liver. It helps bugger ph by binding free h+ in blood serum. Albumins = 60%, keeps lipids in blood stream from clotting. They generate colloid osmotic pressure (prevents swelling in tissue by sucking water back into blood stream. Globulins = 35%, have subtypes (alpha, , gamma), insoluble in water but soluble in dilute salts. Fibrinogen = 4%, helps clog blood with its caging mechanism. Is cleaved to form the active blood clotter, fibrin by thrombin, an enzyme: glucose, lipids (tags, hdl, ldl, glycerol, nitrogenous wastes.
