BIO230H1 Lecture Notes - Lecture 18: Tectorial Membrane, Basilar Membrane, Action Potential

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22 Dec 2019
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BIO230H1 Full Course Notes
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Cells & tissues, after forming, are continually regenerating: molecular turnover within the same cell, we get new molecules (new rna, new proteins etc. , cellular turnover. Auditory hair cells specialized architecture that allows us to hear. Stereocilia contact the tectorial membrane (a mass of ecm); can send signals to nerve fibres. Sound causes vibration of the basilar membrane, causing the stereocilia to tilt; with tilting, tethers pull open ion channels on neighbouring stereocilia, which initiates a nerve impulse. In mammals, hair cells do not re-grow (however, the molecules made will continually be made and destroyed) Light passes through the ganglion cells and interneurons to the rods & cones. Signal is sent forward to the interneurons and ganglion cells; the ganglion cells send this signal backwards to the nerves. Synaptic region region where the rods/cones communicate with the interneurons. Discs of photoreceptor membrane inside the cell; lots of transmembrane proteins to help it detect light.

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