BIO220H1 Lecture Notes - Lecture 4: Effective Population Size, Inbreeding Depression, Heterozygote Advantage

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17 Feb 2017
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BIO220H1 Full Course Notes
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BIO220H1 Full Course Notes
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Intraspecific genetic diversity: heterozygosity, between individuals in same population, between populations of same species. Those are the three different types of variation. Chance changes in the frequency of genes increases in size. Loss of genetic variation allele fixation. Inbreeding becomes common: heterozygosity is reduced, individuals more likely to mate with individuals with whom they are genetically related. Loss of heterozygote advantage for fitness as more individuals become homozygous. Because of reduced fitness less individuals in the population (consequence of loss of heterozygote advantage) this again results in loss of heterozygosity. The variability in population growth rate due to random events such as reproduction and survivorship. Genetic drift vs demographic stochasticity: both in small population, both have a lot to do in random chance and random fluctuations. Genetic drift involves: random sampling of alleles that changes the allele frequency: going through bottleneck should have reduced ne size and evolutionary trajectories are determined by.

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