BIO130H1 Lecture 3: BIO130H1 Lecture 5-6 (Week 3)
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BIO130H1 Full Course Notes
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Eukabyoticnucleus-e. in closed by nuclear envelope nucleus of typical interphase cell is composed of chromatin. 23 pairs of chromosomes chromatin : each chromosome contains a single , long , linear dna molecule and associated proteins. Dna must still be accessible for transcription , replication , and repair. 12 nm in diameter ) nucleosome core particle made up of dna wrapped around core histones. 10 nm in diameter looped domains t protein scaffolds. Nucle0s0me# basic structural unit chromatin isolated from cell in interphase p b. Wrapped nearly twice around core particle histone : small proteins rich in lysine and arginine. It ) charge neutralizes f- ) charge of. I important to neutralize charge b/c like charges repel ) (cid:8869) 2 polypeptide chains that are different but work together histonetailsi usually at amino end. Dna molecule has been packaged into a mitotic chromosome that is.
