BIO130H1 Lecture Notes - Lecture 4: Chromatin, Exonuclease, Primase

• School: UTSG
• Department: Biology
• Course: BIO130H1
• Professor: Kenneth Yip

Document Summary

Euchromatin: relatively non-condensed chromatin: euchromatic regions of interphase chromosomes. Regions where genes tend to be expressed: covalent modification of histones, the presence of chromatin remodeling complexes, and rna polymerase (transcription) complexes modulate the reversible switching from euchromatic to heterochromatic regions. Chromosomes are in very discrete, specific locations in the nucleus. Not enough space in the nucleus to dncondense entire gene: + trsnscription: only the genes wanting to be transcribed are unpacked, transcription: genes are too tightly packed away for transcription. Dna replication: chromatin is remodelled to alter access to dna, transcription factories: regions of nucleus. Lots of dna polymerase, lots of substrate, lots of materials. Mother cell: the cell before (parental divide) Blue strands and red strands mix to create two daughter cells with: direction of dna replication: all 3 are found in nature complementary genetic material. Unidirectional growth of single strands from two starting points. Unidirectional growth of two strands from one starting point.