PSYC62H3 Lecture Notes - Lecture 4: Nitric Oxide Synthase, Nicotine Gum, Sehar

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A gas that functions as a neurotransmitter and gets through the intracellular space via diffusion. It has an impact in different ways one way is through a feedback mechanism for telling a pre- synaptic neuron whether a post synaptic neuron has fired or not, and this strengthens the synapse. Neurons that are down wind do not have one way communication, and this is because of no which strengthens or weakens the synapse by changing the amount of neurotransmitter that is stored and released. These molecules are derived by way of an enzymatic action, obtained by way of our diet. It is made by nitric oxide synthase converts l-arginine into no. In comparison to other neurotransmitters, it is not stored in vesicles, it does not bind to receptors, it goes right through the bilayer and interacts with intracellular components and has impact within. Molecules that have been identified to promote the survival of the organism or the plasticity of neuronal synapses.

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