PSYC62H3 Lecture Notes - Lecture 4: Nitric Oxide Synthase, Tryptophan Hydroxylase, Raphe Nuclei
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1. synthesized with enzymes: a. tryptophan hydroxylase b. L-amino acid decarboxylase: neurons located in raphe nuclei and terminate throughout the brain acetylcholine. 1. synthesized with: acetylcholine transferase a. i. combines choline and acetyl coa. 2. receptors a. ionotropic a. i. nicotinic: metabotropic b. i. muscarinic, broken down with, acetylcholinesterase neuropeptides, protein or amino acid sequences that have an impact on nervous system. 1. it is a gas but functions as a neurotransmitter. 2. synthesis: nitric oxide synthase a. i. converts a. i. 1. 2. two examples of elimination: half life elimination a. i. how much time does it take for a drug to be reduced to half a. ii. Aka first order kinetics b. linear elimination b. i. e. g. ethanol b. ii. 7. inverse agonist: g protein remains bound types of action at an ionotropic receptor, agonist, antagonist, partial agonist antagonists. 1. chronic drug use a. repeated use of a drug typically occurs on a daily basis.
