BIO380H5 Lecture Notes - Lecture 17: Neural Cell Adhesion Molecule, Dermis, Dorsal Root Ganglion
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Bio 380 lecture 17 the neural crest. During neurulation, the neural groove is formed, where the neural tube is folded. As the neural tube forms, the neural crest emigrate to the top of the tube, and the ectoderm on top is healed. In the picture: the dark spaces are filled with hyaluronic acid. The development of the neural crest consists of four main terms: origin, induction, specification and migration. The neural crest originates from the two lateral epithelial cells of the neural plate (ectoderm) The second step is the epithelial to mesenchymal transform, which will allow the cells to emigrate. Induction is done by the nearby cells from the neural tube (the neural crest is part of the neural groove) The cells will then have to move from away from on top of the neural tube via migration. Some of the cells start to differentiate, though some will further differentiate at their destination. The ectodermal cells are rich in bmp.
