BIO315H5 Lecture Notes - Lecture 4: Rod Cell, Platelet, Guanylyl Cyclase
Document Summary
Lecture 4: g protein-coupled receptor (gpcr) and enzyme-coupled receptor signaling (chapter 15, pp. Calmodulin: a ca2+ binding protein that helps relay cytosolic ca2+ signal. Creb) and in this way activate or inhibit the transcription of specific genes. N. s: another property of cam-kinase ii is that the enzyme can use its intrinsic memory mechanism to decode the frequency of ca2+ oscillations, g proteins can directly activate or inactivate ion channels to change ion permeability. G proteins and ion channels (electrical excitability) A rod photoreceptor is a highly specialized cell with outer and inner segments, a cell body, and a synaptic region where the rod passes a chemical signal to a retinal nerve cell. This nerve cell relays the signal to another nerve cell in retina, which in turn relays it to the brain. Gpcr desensitization target cell: 3 modes of adaptation for gpcrs: interact with g proteins. Receptor inactivation: they become altered so that they can no longer.
