BIO315H5 Lecture Notes - Lecture 1: Diglyceride, Multicellular Organism, Cyclic Adenosine Monophosphate
Document Summary
Lecture 1: mechanisms of cell communication (chapter 15, pp. Why is cell communication important: allows organisms to respond to changes in their environment, including the presence of other cells. Mating-deficient yeast mutants include those lacking expression of gpcrs, g. A typical intracellular signaling pathway proteins, kinases, etc. space: endocrine: an endocrine cell secretes the ligand (hormone) into the bloodstream for distribution throughout the body. The hormone can affect any target cell expressing the appropriate receptor. In a multicellular organism, cells communicate with other cells in the organism by producing outgoing signals and responding to incoming signals. Extracellular signal molecules can act over short or long distances; classes of the cell. intercellular signaling: contact-dependent: a membrane-bound ligand molecule communicates with a neighbouring cell; requires direct membrane-membrane contact. Communication between immune cells; embryonic development: paracrine: the ligand is secreted by the signaling cell and diffuses a short distance to bind to receptors on target cells.