PHA 3112 Lecture Notes - Lecture 2: Disseminated Intravascular Coagulation, Intermittent Claudication, Venous Blood
12 Mar 2018
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Reduction in blood flow to tissues by arteries (=ischemia: any reduction in supply of o2 = hypoxia; due to, anemia (reduction in hemoglobin, arterial obstruction. Reduction in blood flow from tissues by veins: interferes w/removal of waste, co2, and causes edema, called: venous engorgement or obstruction. Reduction of lymph flow: excess fluid/plasma capillaries, interstitial spaces, and lymphatic vessels, interferes w/immune system, blockage called: lymphedema. : stationary clot in artery, vein or on wall of heart. Made of: aggregated platelets, clotting factors, fibrin. After an mi or after damage/replacement of heart valves. Arterial: reduce flow + increate turbulence, enhances thrombus enlargement, decreased distal flow ischemia, (ex. Venous: impaired removal of wastes + producing swelling (edema, inflammation in a vein (phlebitis) thrombus (thrombophlebitis, needle/catheter, systemic derangement of coagulation disseminated iv coagulation. Arterial: intermittent claudication (pain w/activity, limb cold + cyanotic. Venous: none/edema/life threatening pulmonary embolism, calf/groin tenderness/swelling. Dehydration, heart failure, shock, dysrhythmias, aging, trauma, surgery, smoking, arteriosclerosis, sedentary lifestyle.
