HSS 4102 Lecture 21: Endocrine disruptors III
Document Summary
Hss4102 lecture 21 endocrine disruptors iii. Beneficial (angiogenesis inhibitor used against cancer) and detrimental. Linked to mental, motor, and developmental issues, male genitalia malformations, and more issues (in development/pregnancy). Used in cosmetics, plastics, fragrances, air fresheners, etc. Developmental estrogen syndrome is manifest in climbing breast cancer rates and testicular dysgenesis. Cross section of seminiferous tubules from the testes of a control rat and a rat whose grandfather was born from a mother who had been injected with vinclozolin. Right almost no sperm in the seminiferous tubules. Environmental toxins are effecting our health and nutritious status. Video: pesticides in food affect male fertility: water bottles, chemicals in these plastic, can give estrogenic like effects, male sperm rates are declining. Possible chain of causation leading to demasculinization of male frogs and the decline of frog populations in regions where atrazine use is prevalent: human cyp19 gene > aromatase, meningitis in a leopard frog. Atrzine-induced immunodeficiency in frogs (comperable with aids in humans)