HSS 2305 Chapter Notes - Chapter 14+15: P53, Cyclin-Dependent Kinase 2, Cytoskeleton

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85000 chemicals 7000 high chemical no safety guaranteed. All the chemical that actually comes to ourselves + waste products. 200 different in our bodies but not toxicity. Urine, blood, amniotic fluid, cord blood, breast milk measurable chemical molecules. Endocrine disruptor interferes how much produced, sent by messengers. Requirement of careful control of on/off switch foreign chemicals with interference will give dramatic effect in our health. Bisphenol a(bpa) plastics that is used in all kinds of product -> block of baby bottle in france. Leading into baby with high behavioural disorder cancer eg. more breast cancer patients. Phthalates: interfere with male sex hormone whole change with testosterone level change- the cascade change - anal genital distance change close to female/less male general tract. Significant effect on health to animals same goes to humans. Needed in embryo development & maintenance of differentiated cellular phenotypes, metabolisms, & cell death.

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