BIO 3170 Lecture Notes - Lecture 7: Mobile Genetic Elements, Alu Element, Transposable Element
10 Oct 2016
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Recombination: meiosis: homologous recombination and repair of dna double breaks, dna repair: homologous and non-homologous recombination, restart of stalled or damaged replication forks, dna rearrangements: mobile genetic elements. Barbara mcclintock was awarded the 1983 nobel prize in physiology or medicine. Mobile genetic elements were first described in the late 1940s in the maize genome where they are very active and abundant (49-78% of the maize genome is made up of retrotransposons). Linked regions of the chromosome and physical traits. : transposable elements are segments of dna that encode enzymes and other proteins that mediate the movement of dna within genomes (intracellular mobility) or between bacterial cells (intercellular mobility). Transposable elements are mostly neutral or deleterious. In the human population, no role attributed and so that there is no selection pressure to keep them and many have remained just by chance: they are useful as proxy for neutrally evolving sequence. Plasmids - respective dna can integrate the host genome.
