BIO 1140 Lecture Notes - Lecture 5: Vacuole, Cotransporter, Electrochemical Gradient

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Passive transport molecules move with their diffusion gradient from an area of abundance to an area of low abundance. Non polar molecules can get through the membrane quite easily. Polar molecules can only get through if they are relatively small i. e. water. Charged ions cannot get through membrane: simple diffusion molecule moves through membrane with its, facilitated diffusion moves through membrane with the diffusion gradient but requires some sort of transport protein to transfer across the membrane. A maximum rate can be reached when all transporters are occupied. Competitive inhibition is possible in only facilitated diffusion. To determine whether its simple or facilitated you use your judgment of the partition coefficient which is the ratio of solubility of the molecule in a nonpolar solvent to its solubility in water. Substances that are more soluble in non-polar solvent will pass through the membrane more readily than water-soluble molecules. Outer part of channel there are hydrophobic amino acid which holds the.