BIO 1140 Lecture Notes - Lecture 17: Dna Mismatch Repair, Transcriptomics Technologies, Exact Sequence
16 Oct 2016
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Document Summary
Telomerase has both template and protein activity. Dna damage can happen anytime during the cell cycle: during synthesis: places incorrect nucleotide, when agents damage your dna (coming from outside the body or created inside your body) Dna polymerase reverses and removes the most recently added bases when mispaired. Then resumes dna synthesis in the correct direction. Despite of proofreading and mismatch repair mutations still arise due to evolution. Like continuous dna synthesis except its continuous rna synthesis. Starts at one location and ends at another location (fixed locations) A gene codes for a protein (but not always) Genetic and reflected the lack of understanding of dna or rna (i. e phenotype) regardless of the codons (can be rna too) Cis acting: usually a dna sequence only functional in one region. Trans-acting: protein, when you move a protein it can still function nucleotide bases that encodes a product (an rna like rrna or finally coding for protein).
