KIN110 Lecture Notes - Lecture 22: Partial Pressure, Bronchiole, Perfusion

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Structural characteristics of the respiratory membrane we"re at. Type 1 cells are squamous epithelial (type 1 is the dominant type in alveoli) Oxygen is carried in the serium of the blood, will diffuse through the. Basement" of the cell and then through the vessel wall into the blood stream. Pneumonia >>>> uid uptake, increased thickness and decreasing rate of gas exchange. Surface area of the alveoli are huge, surface area of the lung is approx. 40 times that of the skin, approx 140m^2 if healthy, large sa needed to carry out diffusion. Emphysema, tumors, mucus and in ammatory material decrease this area and inhibit effective oxygenation of the blood. It is the coupling between the amount of gas reaching the alveoli and the blood ow in pulmonary capillaries. Arterial diameter is based on po2 (partial pressure of o2): in alveoli where veintialation is poor, po2 is low and arterioles constrict>>>>blood redirected to where po2 is high (arterioles dilate)

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