KIN202 Lecture 11: Unit 7 Skeletal Muscle Fatigue Part 1
20 Jan 2019
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Kin 202 unit 7 skeletal muscle fatigue: cellular mechanisms part 1. Hallmarks of muscle fatigue changes in muscle contractile properties/performance. Task (exercise) properties and muscle properties that determine time to exhaustion. Reversible decline of muscle performance during activity. Muscles get weaker and slower: reduction in the force and power, slowing of shortening velocity and relaxation that a muscle or group of muscles can generate following exercise. Most recovery occurs within the first hour. There is a slow reversible component that can take several days to reverse: prolonged low-frequency force depression. Very slowly reversible decline of muscle performance: getting rid of damaged proteins and generating new proteins take long (to recover) Characterized by sarcomere disorder, membrane damage and inflammation. Recovery may involve activation of satellite cells and regeneration of damage fibres. Often occur when muscle generate force by lengthening = eccentric. Structural damage following heavy resistance exercise and eccentric contractions. Changes in isometric twitch characteristics and mvc with fatigue.
