BIOL 2420 Lecture Notes - Lecture 10: Carbonic Anhydrase, Autoregulation, Mast Cell
8 Mar 2018
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Unit 1: cardiovascular physiology (j: control of blood vessels, intrinsic autoregulation (the vessels does it himself, adjusts to its needs, myogenic control: Brain, heat & kidney have this function. The muscle cells adjust their diameter so to control the flow of blood. H+ + hco3: active hyperemia, autoregulation and exercise: High co2 = high h+ & k+ (because of increased activity)---no is released to these sites. Perfusion = movement of incoming blood to a tissue. When an occlusion blocks the vessel, perfusion is decreased: this is remedied in the same way metabolically active tissues are remedied, vasodilation occurs, non-metabolic chemical mediators. It"s a potent vasoconstrictor: they"re released from endothelium cells, opens ca2+ channels (these are non-stretch sensitive causes vasoconstriction so the tissues downstream aren"t bombarded with oxygen and nutrients unnecessary. Histamine: released from & stored in mast cells & basophils. It"s a potent vasodilator: epinephrine is released so as to cause vasoconstriction.
