CMMB 413 Lecture Notes - Lecture 1: Mitochondrial Disease, Nuclear Dna, Fundamental Theorem Of Arithmetic
18 Jan 2019
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Mtdna (mitochondrial dna, strictly contains maternal genome) Half of our entire genome is made of repetitive sequences, which are classified based on their location, number of repeats, and how many times they are found (clusters) Defective cell divisions lead to abnormal number of chromosomes in daughter cells. Rna is an intermediate between dna and protein. There are multifactorial processes that are causing known disorders. Many of these disorders are a result of mutations in rna. 22 pairs are autosomes (number from largest size to smallest size) Structurally different than nuclear dna (other resource) Genome: all the genetic material and information that is within an organism. There is a potential intelligence gene located on x chromosome. Chromosomes in mitosis phase have a butterfly shape. Is circular, similar to bacterial dna, therefore theory is that bacterial dna and mtdna underwent endosymbiosis (mtdna grew out of bacterial dna).
