NUTR100 Lecture Notes - Lecture 1: Aldehyde Dehydrogenase, Alcohol Dehydrogenase, Endoplasmic Reticulum
13 Dec 2017
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Document Summary
Distilled spirit has about 12 to 14 kcal per gram. Alcohol is mainly absorbed in the duodenum and jejunum. But large amount of alcohol is also absorbed in the stomach. Since it can be absorbed almost immediately, reactions are very quick. Less alcohol is absorbed when gastric emptying is slower. Alcohol is a toxin so it cannot be stored into the body. Alcohol is given metabolic priority in the liver because it is a toxin. Alcohol can cause dehydration it acts as a diuretic when it reaches the kidneys. This fatty acid is deposited in the liver. Meos comes from microsomes (vesicles break from endoplasmic reticulum). Alcohol can be metabolized by the bacteria in the large intestine. The level of blood alcohol is more on women than men when both consume equal amounts of alcohol. Two hypotheses are: women may have lower activities of alcohol dehydrogenase, they have more body fat and less body water.
