BIOL 102 Lecture Notes - Lecture 6: Endocytosis, Endomembrane System, Facilitated Diffusion

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Peripheral membrane; associated with the either the head of the protein or part of the glycoprotein. Integral membrane proteins transmembrane proteins, lipid membrane proteins- Noncovalently bound to integral membrane proteins or to the polar head groups of. Proteins are important to membrane structure and function. The transmembrane protein can have different affinities to the bilayer and become either tightly or loosely connected. Length of fatty acyl tails: shorter tails more fluidity. Presence of double bonds in acyl tails: more db more fluid. Presence of cholesterol: more cholesterol less fluidity, effects depend on temperature. At 0 degc labels stay still, at 37 degc label moves all over. Covalently attach carbohydrate to a protein or lipid. Serves as recognition signals and cell surface recognition. Protective effects: cell coat (glycocalyx): carb rich zone shields cell. Transmission electron microscopy (tem), uses sample stained with heavy metal dyes. Dyes bind tightly to phospho heads but not to the fatty acyl chains.

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