BIOL 318 Lecture Notes - Lecture 19: Lymphadenopathy, Cytotoxic T Cell, Mhc Class Ii
19 Nov 2018
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Document Summary
Interaction of b7 on apc with cd28 of th cell delivers costimulatory signal. Ii: to activate tc, the dendritic cell must present ag in association with mhc class. I: na ve t cells are characterized by, condensed chromatin, very little cytoplasm, little transcriptional activity, large-scale re-circulation from blood to secondary lymphoid tissues and back (cycle. Interaction with cytokines released at the site of inflammation / infection via their. T cells: cytotoxic t cells help avoid accidental induction of ctls directed towards non- pathogenic or self ags, process, activation of ag-specific th, dc cross-presentation of ag onto class i mhc to activate ag-specific tc, primary response: Thursday november 15th 2018: activation of na ve t cells (th or tc) upregulates expression of il-2 and high affinity. If lymphocyte is still being stimulated by ag, the apoptosis signal is blocked: superantigen-induced th cell activation, superantigens: viral or bacterial proteins that bind simultaneously to both tcr and class.
