PHGY 209 Lecture Notes - Lecture 10: Myeloblast, Eosinophil, Phagocyte

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Clots break down and disappear as healing occurs and blood flow resumes. Fibrin network is broken down by a plasma protein known as plasmin. Plasmin is present in plasma as an inactive precursor known as plasminogen. Plasminogen fragments the network into small pieces which are washed away as blood flow resumes. The plasminogen activation results from the presence of a number of plasminogen activators which are released by the endothelium (lining of the blood vessels), and some by tissues. Plasminogen gets incorporated into the clot as the clot forms. Plasma contains plasminogen and it will then become gradually activated. Primary organs (before birth) o stem cells from the yolk sac and fetal liver o bone marrow o. Secondary organs o lymph nodes o spleen: mucosa-associated lymphoid tissue (malt) Smallpox was a deadful infectious disease that, for many centuries, killed one out of ten people.

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