PHGY 209 Lecture Notes - Lecture 9: Lymphocyte, Pathogen-Associated Molecular Pattern, Dendritic Cell
14 Oct 2017
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Organs of the immune system: primary organs, stem cells from the yolk sac and fetal liver, bone marrow, thymus gland, secondary organs, lymph nodes, spleen, mucosa-associated lymphoid tissue (malt) Everything begins in the yolk sac and then becomes specialized . From the yolk sac, these immune cells go to the fetal liver. The secondary organs also form in utero before birth: Lymph nodes, the spleen (largest lymph node), and mucosa-associated lymphoid tissue (malt) under the gut mucosa, bronchial mucosa, in tears all mucous membrane. Think of self as donut: skin on the outside, mucous membrane on the inside. Have to protect the inside and outside of the donut to avoid attack. Smallpox: dreadful infectious disease that for many centuries killed 1/10 people. Edward jenner noticed milkmaids did not get smallpox and instead had pox marks on their hands (cowpox). Took pus from the cow and was used as vaccine for smallpox.
