PHAR 303 Lecture Notes - Lecture 5: Queen'S Privy Council For Canada, Animal Testing, Public Campaign

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Animal biology: often we use animals to test if a chemical is toxicant. High doses: the issue is that you need lot of material and lot of chemicals to do the experiment. Expensive: the cost for one rat is high --> the minimal price is 40$ and can go up to 400$. They also have to live, so it costs sh. 40-sh. 50 cents per day to feed them and take care of them. Societal concerns: there is pressure from animal rights activists about how to use animals in studies. Knowledge: we can get into targets and mechanisms more easily in animals and understand how a chemical works. Money: in vitro tests cost less, they grow more rapidly, and it is easy because you only need to buy the initial cell line. Speed: can build and screen everything very fast. Efficiency: can screen up to 200 chemicals in 1 or 2 days. Ethics: we have to consider the ethical issues as well.

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