LSCI 204 Lecture Notes - Lecture 8: In Situ Hybridization, Gamete, Chromosome
8 Feb 2018
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Chapter 5: linkage, recombination, and eukaryotic gene mapping. Principle of segregation: alleles separate during meiosis. Independent assortment: alleles at one locus sort independently from alleles at another locus. Alfred henry sturtevant, an early geneticist, developed the first genetic map. Genetic map of five genes on the x chromosome of drosophila. Recombination is the sorting of alleles into new combinations: the independent separation of alleles results in recombination, the sorting of alleles to new combinations, consider a cross between individuals homozygous for two different pairs of alleles: The first parent, aa bb, produces gametes with the alleles a b. The second parent, aa bb, produces gametes with the alleles a b. Recombination when one of the f1 progeny reproduces, the combination of alleles in its gametes may differ from its parents. F1 may produce gametes with new combinations of alleles a b or a b, and also to parental gametes with a b or a b.
