BIOL 2201 Lecture Notes - Lecture 7: Treadmilling, Golgi Apparatus, Endoplasmic Reticulum
8 Dec 2017
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Document Summary
Some eukaryotic or prokaryotic use cytoskeleton for movement. Is composed of 3 types of protein filaments which are intermediate filaments, microtubules, and actin filaments. Each of these filaments have its unique properties. Each type is composed of unique protein subunits which assemble by polymerization. For it to function it needs to extend and shrink. Typically have one end attached to a microtubule organizing center (mtoc). Grow toward the positive end if they bind to a structure. Can form linear bundels 2d networks or 3d gels. Throughout the cell but mostly in cortex (5-9nm diameter) Monomer for intermediate filaments: (to stand mechanical stress) Alpha helical region of monomer: n-terminal globular head (nh2), rod domain, and c- terminal gloubular tail (cooh) The globular regions vary greatly and interact with cell components. The central rod region of various monomers of intermediate filaments remain very constant.
