SCIE 1P51 Lecture 13: lecture 13
6 Apr 2016
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Document Summary
Tissue engineering: regenerative medicine, spare parts , ancient practice oldest found spare parts come from a female mummy (big toe, 3d printed body parts 2016 customized prosthetics. What is it: the application of engineering and genetics toward the development of biological substitutes to restore, maintain, or improve functions of human tissue. Basic tools: cells, proteins growth factors, extracellular matrix (ecm, scaffolds. Cells: not all cells have equal potential to regenerate, high skin cell injuries, moderate bone injuries, low heart cells. Stem cells: have a unique ability to renew themselves and give rise to the more specialized cell types. They remain undifferentiated until a protein/chemical factor initiates change. Cells: somatic/ gamete cells are differentiated, hence have to be renewed, stem cells are also renewed or can become differentiated. Source of cells: autologous from patient, allogeneic- from another member of the same species, xenologous form another species. Cell types: stem cells different potentials. Unipotent adult/ eg. skin stem cells.
