SCIE 1P51 Lecture Notes - Lecture 11: Biomaterial, Embryonic Stem Cell, Epithelium
22 Mar 2016
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Document Summary
Spare parts - replace functionality when our own tissues stop working (ex. heart attack) Ancient practice - female mummy (950-710 bce) Made for functionality but also ascetic perspective. 2016 3d printed body parts - 3d printers to customize prosthetics, instead of ink they use cells. The application of engineering and genetics towards the development of biological substitutes to restore, maintain or improve functions of human tissue. Using biology of how cells work, using technology to plant it into the human and make it function again. Extracellular matrix (ecm) - replicate that body environment outside of the lab. Scaffolds - grow cells in the right environment (on scaffolds), arrange in a particular structure. Natural biomaterials (things taken out of nature) Synthetic biomaterials (things we can break down and control the size of) Cells - biomaterial/scaffold - scaffold + cells. Not all cells have equal potential to regenerate. Without catastrophic damage cells can regenerate but may not function the same.
