BIOL 3P30 Lecture Notes - Lecture 1: Apoptosis, Gps Exchange Format, Reactive Oxygen Species
4 Apr 2016
School
Department
Course
Professor
Document Summary
The following are questions that you should be able to answer in some detail. If you can answer all of them completely you will do well on the midterm! Post translational modifications regulate specific activity of protein (1 or more copy of a protein; amount of event performed per unit time/ molecule of that protein) Also cleavage of internal domain: protein is folded so its blocking the active site, this piece is cleaved when the protein needs to be activated. Proteins in inner membrane affected by the phospholipids around them (ex some need cardiolipin to be active) Transcription: regulated by repressor and enhancer which are usually found upstream of the gene. Protein binds to this and either enhancer (increase rate of transcription) or repress transcription. Enhance by interacting with tf and rna pol, rna processing (splicosomes ect) Tf is assembled at the tata box (dna sequence) Proteins in transcription: alter chromatin structure, initiate transcription (tf, rna pol), elongation,
