BIOL 3P30 Lecture Notes - Lecture 8: Torpor, Gas Exchange, Cycloheximide

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Rolfe and brown calculate the contributions of different atp consuming reactions to standard metabolic rate (smr): In mammals the major contributors to smr are liver, heart, brain, skeletal muscles, and. There are three major contributors to cellular atp consumption: Issues with these experiments-the poison will kill the cell. The key of the experiment is to acutely stop synthesis. ~ 60% of mitochondrial o2 consumption can be accounted for by just four processes: proton leak, na/k. This is whole body smr determined by: % of body constituted by particular cell type or organ x measured values for that cell type or organ. Protein synthesis o o costs could be super high o o o actively mitotic cells o. 5-30% of cell atp use (depends on tissue) Many atp used to build a single protein. Many made at the same time so energy. 3-74% of cell atp consumption: high in epithelial cells and other metabolic depression =

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