HSBH2008 Lecture Notes - Lecture 20: Oxidative Stress, Vo2 Max, Hayflick Limit
22 Aug 2018
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Defining ageing : sum of all changes that occur with the passage of time a complex interaction between physiologic, genetic, molecular, behavioural & environmental factors which can interact simultaneously. Wold health organisation definition: elderly: 60-74 years, old: 75-84 years, very old: 85+ years. Lifespan vs health span: we have to differentiate between lifespan and health span. Rate of decline in vo2max: there are many physiological changes associated with ageing. These can be musculoskeletal, cardiovascular, neurological etc: there is a decline in vo2max of ~30% between 20-65 years (greatest decline after age 40). After age 70: >20% decline per decade but: no more than. Age-related physiological changes in a nutshell (bidirectional causality: age related decline affects ability to do pa. Multiple treatments cause harm and contribute to geriatric syndromes: 66% of australians aged >75 take at least 5 different medicines a day, 43% of australians aged >50 take at least 5 different medicines a day.
