EXSS2026 Lecture Notes - Lecture 7: Bone Density, Synovial Membrane, Menopause

• School: University of Sydney
• Department: Exercise and Sport Science
• Course: EXSS2026
• Professor: Nathan Johnson

Document Summary

Theories: glycation stress, exhaustion of dividing cells (hayflick limit, free radicals oxidative stress/damage, telomere shrinkage (neo-hayflick) Telomeres & slowing ageing: telomere shortening, longer telomere = more capacity to replicate longer, pa moderates telomere length. Ageing & disability: ~8 years for women, ~6 years for men, focus is on how to increase healthy ageing, prolong lifespan vs. healthy life. Ageing trends & theories key points: population is ageing rapidly, lifespan is getting longer, healthspan doesn(cid:495)t follow, population theories about free radicals & telomere shrinkage, pa may beneficially influence anti-oxidant production & telomere length. Except bp and hr: people are ageing and becoming less active is this due to ageing or physical inactivity, resveratol can decrease the risk of disease, 28% increased risk when drinking (risk increases. Increase the risk of death/cancer with drinking with regular drinking: no risk if drink with pa (if meet pa guidelines, structural, increased lipid content (atherosclerosis, functional, decreased baroreceptor sensitivity, decreased hrmax.