BIOS1167 Lecture Notes - Lecture 11: Nucleoside Triphosphate, Sister Chromatids, Dna Replication

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Every cell contains dna blueprint in its chromosomes (genome) Determines characteristics and encodes information for protein synthesis. Exact duplication of the entire genome of the cell. Separation of two daughter genomes = mitosis. Division of cell into two new cells = cytokinesis. Phases: interphase cell growth and prep > dna replication > prep for mitosis, mitosis separation into 2 daughter nuclei, cytokinesis division into 2 daughter cells. Double helix is opened up > copies made of both strands > two daughter helices are created. = one old strand and one new strand (one chromatid and sister chromatid) Replicate large amounts of dna simultaneously by using multiple origins of replication. Accurately matches dna bases to complementary nucleotide bases (a>t) (c>g) (cid:396)e(cid:395)ui(cid:396)es a (cid:858)p(cid:396)i(cid:373)e(cid:396)(cid:859) portion of dna to get started. Structures on the ends of a strand of chromosomes. A longer telomere = longevity of life due to a better ability of cells to divide. Ageing is associated with shorter telomere length.

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